The FDA-cleared BIOFIRE JI Panel is a comprehensive diagnostic test that identifies 39 clinically relevant targets from synovial fluid. This syndromic panel detects bacteria, yeast, and antimicrobial resistance genes, helping to reduce the time to effective therapy through rapid pathogen identification.1
Gram-Negative Bacteria
- Bacteroides fragilis
- Citrobacter
- Enterobacter cloacae complex
- Escherichia coli
- Haemophilus influenzae
- Kingella kingae
- Klebsiella aerogenes
- Klebsiella pneumoniae group
- Morganella morganii
- Neisseria gonorrhoeae
- Proteus spp.
- Pseudomonas aeruginosa
- Salmonella spp.
- Serratia marcescens
Yeast
- Candida spp.
- Candida albicans
Gram-Positive Bacteria
- Anaerococcus prevotii/vaginalis
- Clostridium perfringens
- Cutibacterium avidum/granulosum
- Enterococcus faecalis
- Enterococcus faecium
- Finegoldia magna
- Parvimonas micra
- Peptoniphilus
- Peptostreptococcus anaerobius
- Staphylococcus aureus
- Staphylococcus lugdunensis
- Streptococcus spp.
- Streptococcus agalactiae
- Streptococcus pneumoniae
- Streptococcus pyogenes
Antimicrobial Resistance Genes
- Carbapenemases
- IMP
- KPC
- NDM
- OXA-48-like
- VIM
- ESBL
- CTX-M
- Methicillin resistance
- mecA/C and MREJ (MRSA)
- Vancomycin Resistance
- vanA/B
Technology: Multiplex PCR-based molecular diagnostics (syndromic approach)
Format: Single, self-contained, freeze-dried reagent pouch
Sample Type: Synovial fluid
Result Time: Approximately one hour
Ease of Use: Automated workflow from sample to result, requiring minimal hands-on time
The BioFire Joint Infection Panel is a powerful tool for the diagnosis of patients suspected of having joint infections. By providing fast and accurate results, the panel helps clinicians make more-informed decisions about antimicrobial therapy and potentially reduce the need for additional costly and time-consuming diagnostic tests.1
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- Esteban J, et al. Journal of Clinical Microbiology. 25 October, 2023. https://doi.org/10.1128/jcm.00357-23
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